A Multicenter Prospective Diagnostic Test: Screening and Differentiating Common Cancers (Cancers of Lung, Stomach, Colorectum, Esophagus, Liver, Breast and Pancreas) Based on Peripheral Blood Cell-Free DNA Sequencing
Status: Recruiting
Location: See all (8) locations...
Study Type: Observational
SUMMARY
The goal of this observational study is to screen and differentiate common cancers in participants with or without suspicious lesions. The main question the investigators aim to answer is: Can the developed model, using peripheral blood cell-free DNA sequencing, work well in screening and classifying common cancers especially in the early stages? Participants will undergo the collection of 15\ 20ml of blood and 1\ 2 telephone follow-up calls.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Maximum Age: 80
Healthy Volunteers: t
View:
• \>20 and \< 80 years old.
• Cancer group: Newly diagnosed cancer patients with a confirmed pathological diagnosis within 90 days before blood collection or within 30 days after blood collection, including lung cancer, esophageal cancer, breast cancer, stomach cancer, colorectal cancer, liver cancer, and pancreatic cancer.
⁃ Non-cancer group: Individuals who have not been diagnosed with cancer during routine physical examinations and one-year follow-up.
Locations
Other Locations
China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NOT_YET_RECRUITING
Guangzhou
The First Affiliated Hospital of Guangzhou Medical University
RECRUITING
Guangzhou
Guanxian People's Hospital
RECRUITING
Liaocheng
First Hospital of China Medical University
NOT_YET_RECRUITING
Shenyang
Affiliated Cancer Hospital of Xinjiang Medical University
RECRUITING
Ürümqi
First Affiliated Hospital of Air Force Military Medical University
RECRUITING
Xi'an
Tang-du Hospital
RECRUITING
Xi'an
People's Hospital of Ningxia Hui Autonomous Region
NOT_YET_RECRUITING
Yinchuan
Contact Information
Primary
Yanglin Pan, MD
yanglinpan@hotmail.com
86-13991811225
Time Frame
Start Date:2023-09-01
Estimated Completion Date:2025-12
Participants
Target number of participants:3200
Treatments
Multicenter prospective cancer-screening cohort
The cohort, including cancer patients and non-cancer patients, will be prospectively enrolled in from different departments and centers. The focused cancers include lung cancer, gastric cancer, colorectal cancer, liver cancer, esophagus cancer, breast cancer and pancreas cancer.
Collaborators: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, The First Affiliated Hospital of Guangzhou Medical University, Guanxian People's Hospital, Tang-Du Hospital, Xinjiang Medical University, First Hospital of China Medical University, People's Hospital of Ningxia Hui Autonomous Region
Leads: Air Force Military Medical University, China